Package: goldilocks 0.4.0

goldilocks: Goldilocks Adaptive Trial Designs for Time-to-Event Endpoints

Implements the Goldilocks adaptive trial design for a time to event outcome using a piecewise exponential model and conjugate Gamma prior distributions. The method closely follows the article by Broglio and colleagues <doi:10.1080/10543406.2014.888569>, which allows users to explore the operating characteristics of different trial designs.

Authors:Graeme L. Hickey [aut, cre], Ying Wan [aut], Thevaa Chandereng [aut], Becton, Dickinson and Company [cph], Tim Kacprowski [ctb]

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goldilocks.pdf |goldilocks.html
goldilocks/json (API)
NEWS

# Install 'goldilocks' in R:
install.packages('goldilocks', repos = c('https://graemeleehickey.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/graemeleehickey/goldilocks/issues

Uses libs:
  • c++– GNU Standard C++ Library v3

On CRAN:

adaptivebayesianbayesian-statisticsclinical-trialsstatisticscpp

4.54 score 7 stars 4 scripts 24 downloads 10 exports 23 dependencies

Last updated 10 days agofrom:38a7897263. Checks:9 OK. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKJan 09 2025
R-4.5-win-x86_64OKJan 09 2025
R-4.5-linux-x86_64OKJan 09 2025
R-4.4-win-x86_64OKJan 09 2025
R-4.4-mac-x86_64OKJan 09 2025
R-4.4-mac-aarch64OKJan 09 2025
R-4.3-win-x86_64OKJan 09 2025
R-4.3-mac-x86_64OKJan 09 2025
R-4.3-mac-aarch64OKJan 09 2025

Exports:enrollmentppweprop_to_hazpwe_imputepwe_simrandomizationsim_comp_datasim_trialssummarise_simssurvival_adapt

Dependencies:BHclidplyrfansigenericsgluelatticelifecyclemagrittrMatrixpbmcapplypillarpkgconfigPWEALLR6Rcpprlangsurvivaltibbletidyselectutf8vctrswithr

Example: Two-armed RCT

Rendered frombroglio.Rmdusingknitr::rmarkdownon Jan 09 2025.

Last update: 2021-06-27
Started: 2021-03-07