Package: joineR 1.2.8

joineR: Joint Modelling of Repeated Measurements and Time-to-Event Data

Analysis of repeated measurements and time-to-event data via random effects joint models. Fits the joint models proposed by Henderson and colleagues <doi:10.1093/biostatistics/1.4.465> (single event time) and by Williamson and colleagues (2008) <doi:10.1002/sim.3451> (competing risks events time) to a single continuous repeated measure. The time-to-event data is modelled using a (cause-specific) Cox proportional hazards regression model with time-varying covariates. The longitudinal outcome is modelled using a linear mixed effects model. The association is captured by a latent Gaussian process. The model is estimated using am Expectation Maximization algorithm. Some plotting functions and the variogram are also included. This project is funded by the Medical Research Council (Grant numbers G0400615 and MR/M013227/1).

Authors:Pete Philipson [aut], Ines Sousa [aut], Peter J. Diggle [aut], Paula Williamson [aut], Ruwanthi Kolamunnage-Dona [aut], Robin Henderson [aut], Graeme L. Hickey [aut, cre], Maria Sudell [ctb], Medical Research Council [fnd]

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NEWS

# Install 'joineR' in R:
install.packages('joineR', repos = c('https://graemeleehickey.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/graemeleehickey/joiner/issues

Datasets:
  • aids - AIDS drug trial data
  • epileptic - Dose calibration of anti-epileptic drugs data
  • heart.valve - Aortic valve replacement surgery data
  • liver - Liver cirrhosis drug trial data
  • mental - Mental health trial data

On CRAN:

biostatisticscompeting-riskscoxjoinerlongitudinal-datarepeated-measurementsrepeated-measuresstatisicsstatistical-methodssurvivalsurvival-analysistime-to-event

11 exports 17 stars 2.66 score 6 dependencies 6 mentions 66 scripts 618 downloads

Last updated 2 years agofrom:ca1d211395. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKSep 03 2024
R-4.5-winOKSep 03 2024
R-4.5-linuxOKSep 03 2024
R-4.4-winOKSep 03 2024
R-4.4-macOKSep 03 2024
R-4.3-winOKSep 03 2024
R-4.3-macOKSep 03 2024

Exports:jointjointdatajointplotjointSEsample.jointdatasimjointsummarybalto.balancedto.unbalancedUniqueVariablesvariogram

Dependencies:latticeMASSMatrixnlmestatmodsurvival

Competing risks

Rendered fromcompeting-risks.Rmdusingknitr::rmarkdownon Sep 03 2024.

Last update: 2017-07-24
Started: 2017-03-02

joineR

Rendered fromjoineR.Rmdusingknitr::rmarkdownon Sep 03 2024.

Last update: 2021-01-03
Started: 2017-01-05